Statistical Strategies For Small Sample Research

Download or read book Statistical Strategies for Small Sample Research written by Rick H. Hoyle and published by SAGE. This book was released on 1999-03-30 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides encouragement and strategies for researchers who routinely address research questions using data from small samples. Chapters cover such topics as: using multiple imputation software with small sets; computing and combining effect sizes; bootstrap hypothesis testing; application of latent variable modeling; time-series data from small numbers of individuals; and sample size, reliability and tests of statistical mediation.

Download or read book Small Clinical Trials written by Institute of Medicine and published by National Academies Press. This book was released on 2001-01-01 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.

Download or read book Small Sample Size Solutions written by Rens van de Schoot and published by Routledge. This book was released on 2020-02-13 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Researchers often have difficulties collecting enough data to test their hypotheses, either because target groups are small or hard to access, or because data collection entails prohibitive costs. Such obstacles may result in data sets that are too small for the complexity of the statistical model needed to answer the research question. This unique book provides guidelines and tools for implementing solutions to issues that arise in small sample research. Each chapter illustrates statistical methods that allow researchers to apply the optimal statistical model for their research question when the sample is too small. This essential book will enable social and behavioral science researchers to test their hypotheses even when the statistical model required for answering their research question is too complex for the sample sizes they can collect. The statistical models in the book range from the estimation of a population mean to models with latent variables and nested observations, and solutions include both classical and Bayesian methods. All proposed solutions are described in steps researchers can implement with their own data and are accompanied with annotated syntax in R. The methods described in this book will be useful for researchers across the social and behavioral sciences, ranging from medical sciences and epidemiology to psychology, marketing, and economics.

Download or read book Federal Statistics, Multiple Data Sources, and Privacy Protection written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-01-27 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The environment for obtaining information and providing statistical data for policy makers and the public has changed significantly in the past decade, raising questions about the fundamental survey paradigm that underlies federal statistics. New data sources provide opportunities to develop a new paradigm that can improve timeliness, geographic or subpopulation detail, and statistical efficiency. It also has the potential to reduce the costs of producing federal statistics. The panel's first report described federal statistical agencies' current paradigm, which relies heavily on sample surveys for producing national statistics, and challenges agencies are facing; the legal frameworks and mechanisms for protecting the privacy and confidentiality of statistical data and for providing researchers access to data, and challenges to those frameworks and mechanisms; and statistical agencies access to alternative sources of data. The panel recommended a new approach for federal statistical programs that would combine diverse data sources from government and private sector sources and the creation of a new entity that would provide the foundational elements needed for this new approach, including legal authority to access data and protect privacy. This second of the panel's two reports builds on the analysis, conclusions, and recommendations in the first one. This report assesses alternative methods for implementing a new approach that would combine diverse data sources from government and private sector sources, including describing statistical models for combining data from multiple sources; examining statistical and computer science approaches that foster privacy protections; evaluating frameworks for assessing the quality and utility of alternative data sources; and various models for implementing the recommended new entity. Together, the two reports offer ideas and recommendations to help federal statistical agencies examine and evaluate data from alternative sources and then combine them as appropriate to provide the country with more timely, actionable, and useful information for policy makers, businesses, and individuals.

Download or read book Fundamentals of Modern Statistical Methods written by Rand R. Wilcox and published by Springer Science & Business Media. This book was released on 2010-03-18 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conventional statistical methods have a very serious flaw. They routinely miss differences among groups or associations among variables that are detected by more modern techniques, even under very small departures from normality. Hundreds of journal articles have described the reasons standard techniques can be unsatisfactory, but simple, intuitive explanations are generally unavailable. Situations arise where even highly nonsignificant results become significant when analyzed with more modern methods. Without assuming the reader has any prior training in statistics, Part I of this book describes basic statistical principles from a point of view that makes their shortcomings intuitive and easy to understand. The emphasis is on verbal and graphical descriptions of concepts. Part II describes modern methods that address the problems covered in Part I. Using data from actual studies, many examples are included to illustrate the practical problems with conventional procedures and how more modern methods can make a substantial difference in the conclusions reached in many areas of statistical research. The second edition of this book includes a number of advances and insights that have occurred since the first edition appeared. Included are new results relevant to medians, regression, measures of association, strategies for comparing dependent groups, methods for dealing with heteroscedasticity, and measures of effect size.

Download or read book Statistical Analysis Quick Reference Guidebook written by Alan C. Elliott and published by SAGE. This book was released on 2007 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical `cut to the chase′ handbook that quickly explains the when, where, and how of statistical data analysis as it is used for real-world decision-making in a wide variety of disciplines. In this one-stop reference, the authors provide succinct guidelines for performing an analysis, avoiding pitfalls, interpreting results and reporting outcomes.

Download or read book Structural Equation Modeling written by Jichuan Wang and published by John Wiley & Sons. This book was released on 2019-09-05 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a useful guide for applications of SEM whilst systematically demonstrating various SEM models using Mplus Focusing on the conceptual and practical aspects of Structural Equation Modeling (SEM), this book demonstrates basic concepts and examples of various SEM models, along with updates on many advanced methods, including confirmatory factor analysis (CFA) with categorical items, bifactor model, Bayesian CFA model, item response theory (IRT) model, graded response model (GRM), multiple imputation (MI) of missing values, plausible values of latent variables, moderated mediation model, Bayesian SEM, latent growth modeling (LGM) with individually varying times of observations, dynamic structural equation modeling (DSEM), residual dynamic structural equation modeling (RDSEM), testing measurement invariance of instrument with categorical variables, longitudinal latent class analysis (LLCA), latent transition analysis (LTA), growth mixture modeling (GMM) with covariates and distal outcome, manual implementation of the BCH method and the three-step method for mixture modeling, Monte Carlo simulation power analysis for various SEM models, and estimate sample size for latent class analysis (LCA) model. The statistical modeling program Mplus Version 8.2 is featured with all models updated. It provides researchers with a flexible tool that allows them to analyze data with an easy-to-use interface and graphical displays of data and analysis results. Intended as both a teaching resource and a reference guide, and written in non-mathematical terms, Structural Equation Modeling: Applications Using Mplus, 2nd edition provides step-by-step instructions of model specification, estimation, evaluation, and modification. Chapters cover: Confirmatory Factor Analysis (CFA); Structural Equation Models (SEM); SEM for Longitudinal Data; Multi-Group Models; Mixture Models; and Power Analysis and Sample Size Estimate for SEM. Presents a useful reference guide for applications of SEM while systematically demonstrating various advanced SEM models Discusses and demonstrates various SEM models using both cross-sectional and longitudinal data with both continuous and categorical outcomes Provides step-by-step instructions of model specification and estimation, as well as detailed interpretation of Mplus results using real data sets Introduces different methods for sample size estimate and statistical power analysis for SEM Structural Equation Modeling is an excellent book for researchers and graduate students of SEM who want to understand the theory and learn how to build their own SEM models using Mplus.