Rabbit Biotechnology

Download or read book Rabbit Biotechnology written by Louis-Marie Houdebine and published by Springer Science & Business Media. This book was released on 2009-04-24 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Louis-Marie Houdebine and Jianglin Fan The study of biological functions of proteins and their possible roles in the pathogenesis of human diseases requires more and more relevant animal m- els. Although mice including genetically modified mice offer many possibilities, other non-murine species are absolutely required in some circumstances. Rabbit is one of these species, which has been widely used in biomedical studies. This animal is genetically and physiologically closer to humans including cardiov- cular system and metabolism characteristics. Rabbit is thus more appropriate than mice to study some diseases such as atherosclerosis and lipid metabolism. Because of its larger size, surgery manipulation, bleeding, and turn-over studies are much easier performed in rabbits than in mice. Furthermore, transgenic rabbits can be produced using microinjection and other methods such as lentiviral v- tors. Cloning in rabbits has been proved possible, even though still laborious and time-consuming. Hopefully, functional rabbit ES cell lines will be available in the coming years. Gene deletion or knock-out in rabbits will then become possible.

Download or read book The Genetics and Genomics of the Rabbit written by Luca Fontanesi and published by CABI. This book was released on 2021-06-15 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rabbits have many uses - as well as being cherished pets, they are bred for their meat and fur, and as laboratory animals. Understanding their genetics and genomics is key to their production and, equally, to their care, welfare and health. Beginning with an introduction to the rabbit, including key information on their evolution, domestication and breed types, this book then concentrates on the genetics and genomics of this valuable animal. Concluding with practical applications such as creating transgenic and genome edited rabbits, biotechnical applications and the rabbit as a biomedical model, this book brings this important topic fully up-to-date. It provides an indispensable resource for animal and veterinary researchers and students, as well as rabbit breeders and laboratory scientists.

Download or read book Animal Biotechnology written by National Research Council and published by National Academies Press. This book was released on 2002-11-29 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic-based animal biotechnology has produced new food and pharmaceutical products and promises many more advances to benefit humankind. These exciting prospects are accompanied by considerable unease, however, about matters such as safety and ethics. This book identifies science-based and policy-related concerns about animal biotechnologyâ€"key issues that must be resolved before the new breakthroughs can reach their potential. The book includes a short history of the field and provides understandable definitions of terms like cloning. Looking at technologies on the near horizon, the authors discuss what we know and what we fear about their effectsâ€"the inadvertent release of dangerous microorganisms, the safety of products derived from biotechnology, the impact of genetically engineered animals on their environment. In addition to these concerns, the book explores animal welfare concerns, and our societal and institutional capacity to manage and regulate the technology and its products. This accessible volume will be important to everyone interested in the implications of the use of animal biotechnology.

Download or read book Telepresence & Bio Art written by Eduardo Kac and published by University of Michigan Press. This book was released on 2005 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Eduardo Kac's work represents a turning point. What it questions is our current attitudes to creativity, taking that word in its most fundamental sense." -Edward Lucie-Smith, author of Visual Arts in the 20th Century "His works introduce a vital new meaning into what had been known as the creative process while at the same time investing the notion of the artist-inventor with an original social and ethical responsibility." -Frank Popper, author of Origins and Development of Kinetic Art "Kac's radical approach to the creation and presentation of the body as a wet host for artificial memory and 'site-specific' work raises a variety of important questions that range from the status of memory in digital culture to the ethical dilemmas we are facing in the age of bioengineering and tracking technology." -Christiane Paul, Whitney Museum of Art For nearly two decades Eduardo Kac has been at the cutting edge of media art, first inventing early online artworks for the web and continuously developing new art forms that involve telecommunications and robotics as a new platform for art. Interest in telepresence, also known as telerobotics, exploded in the 1990s, and remains an important development in media art. Since that time, Kac has increasingly moved into the fields of biology and biotechnology. Telepresence and Bio Art is the first book to document the evolution of bio art and the aesthetic development of Kac, the creator of the "artist's gene" as well as the controversial glow-in-the-dark, genetically engineered rabbit Alba. Kac covers a broad range of topics within media art, including telecommunications media, interactive systems and the Internet, telematics and robotics, and the contact between electronic art and biotechnology. Addressing emerging and complex topics, this book will be essential reading for anyone interested in contemporary art.

Download or read book Rabbit Production written by George Streator Templeton and published by . This book was released on 1946 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Animals as Biotechnology written by Richard Twine and published by Earthscan. This book was released on 2010 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Animals as Biotechnology sociologist Richard Twine places the question of human/animal relations at the heart of sustainability and climate change debates. The book is shaped by the emergence of two contradictory trends within our approach to nonhuman animals: the biotechnological turn in animal sciences, which aims to increase the efficiency and profitability of meat and dairy production; and the emerging field of critical animal studies - mostly in the humanities and social sciences - which works to question the nature of our relations with other animals. The first part of the book focuses on ethics, examining critically the dominant paradigms of bioethics and power relations between human and non-human. The second part considers animal biotechnology and political economy, examining commercialisation and regulation. The final part of the book centres on discussions of sustainability, limits and an examination of the prospects for animal ethics if biotechnology becomes part of the dominant agricultural paradigm. Twine concludes by considering whether growing calls to reduce our consumption of meat/dairy products in the face of climate change threats are in fact complicit with an anthropocentric understanding of sustainability and that what is needed is a more fundamental ethical and political questioning of relations and distinctions between humans, animals and nature.

Download or read book Monoclonal Antibody Production written by National Research Council and published by National Academies Press. This book was released on 1999-05-06 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: The American Anti-Vivisection Society (AAVS) petitioned the National Institutes of Health (NIH) on April 23, 1997, to prohibit the use of animals in the production of mAb. On September 18, 1997, NIH declined to prohibit the use of mice in mAb production, stating that "the ascites method of mAb production is scientifically appropriate for some research projects and cannot be replaced." On March 26, 1998, AAVS submitted a second petition, stating that "NIH failed to provide valid scientific reasons for not supporting a proposed ban." The office of the NIH director asked the National Research Council to conduct a study of methods of producing mAb. In response to that request, the Research Council appointed the Committee on Methods of Producing Monoclonal Antibodies, to act on behalf of the Institute for Laboratory Animal Research of the Commission on Life Sciences, to conduct the study. The 11 expert members of the committee had extensive experience in biomedical research, laboratory animal medicine, animal welfare, pain research, and patient advocacy (Appendix B). The committee was asked to determine whether there was a scientific necessity for the mouse ascites method; if so, whether the method caused pain or distress; and, if so, what could be done to minimize the pain or distress. The committee was also asked to comment on available in vitro methods; to suggest what acceptable scientific rationale, if any, there was for using the mouse ascites method; and to identify regulatory requirements for the continued use of the mouse ascites method. The committee held an open data-gathering meeting during which its members summarized data bearing on those questions. A 1-day workshop (Appendix A) was attended by 34 participants, 14 of whom made formal presentations. A second meeting was held to finalize the report. The present report was written on the basis of information in the literature and information presented at the meeting and the workshop.