Quantifying Morphology And Physiology Of The Human Body Using Mri

Download or read book Quantifying Morphology and Physiology of the Human Body Using MRI written by L. Tugan Muftuler and published by CRC Press. This book was released on 2013-05-02 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the medical imaging field, clinicians and researchers are increasingly moving from the qualitative assessment of printed images to the quantitative evaluation of digital images since the quantitative techniques often improve diagnostic accuracy and complement clinical assessments by providing objective criteria. Despite this growing interest, the field lacks a comprehensive body of knowledge. Filling the need for a complete manual on these novel techniques, Quantifying Morphology and Physiology of the Human Body Using MRI presents a wide range of quantitative MRI techniques to study the morphology and physiology of the whole body, from the brain to musculoskeletal systems. Illustrating the growing importance of quantitative MRI, the book delivers an indispensable reference for readers who would like to explore in vivo MRI techniques to quantify changes in the morphology and physiology of tissues caused by various disease mechanisms. With internationally renowned experts sharing their insight on the latest developments, the book goes beyond conventional MRI contrast mechanisms to include new techniques that measure electromagnetic and mechanical properties of tissues. Each chapter offers comprehensive information on data acquisition, processing, and analysis techniques as well as clinical applications. The text organizes the techniques based on their primary use either in the brain or the body. Some of the techniques, such as diffusion-weighted imaging and diffusion tensor imaging, span several application areas, including brain imaging, cancer imaging, and musculoskeletal imaging. The book also covers up-and-coming quantitative techniques that explore tissue properties other than the presence of protons (or other MRI-observable nuclei) and their interactions with their environment. These novel techniques provide unique information about the electromagnetic and mechanical properties of tissues and introduce new frontiers of study into disease mechanisms.

Download or read book Quantitative Magnetic Resonance Imaging written by Nicole Seiberlich and published by Academic Press. This book was released on 2020-11-18 with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Magnetic Resonance Imaging is a 'go-to' reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: - The basic physics behind tissue property mapping - How to implement basic pulse sequences for the quantitative measurement of tissue properties - The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* - The pros and cons for different approaches to mapping perfusion - The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor - maps and more complex representations of diffusion - How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed - How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance - Fingerprinting can be used to accelerate or improve tissue property mapping schemes - How tissue property mapping is used clinically in different organs - Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds - Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements - Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges - Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches

Download or read book Quantitative MRI of the Brain written by Mara Cercignani and published by CRC Press. This book was released on 2018-01-12 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building on the success of the first edition of this book, the winner of the 2004 British Medical Association Radiology Medical Book Competition, Quantitative MRI of the Brain: Principles of Physical Measurement gives a unique view on how to use an MRI machine in a new way. Used as a scientific instrument it can make measurements of a myriad of physical and biological quantities in the human brain and body. For each small tissue voxel, non-invasive information monitors how tissue changes with disease and responds to treatment. The book opens with a detailed exposition of the principles of good practice in quantification, including fundamental concepts, quality assurance, MR data collection and analysis and improved study statistical power through minimised instrumental variation. There follow chapters on 14 specific groups of quantities: proton density, T1, T2, T2*, diffusion, advanced diffusion, magnetisation transfer, CEST, 1H and multi-nuclear spectroscopy, DCE-MRI, quantitative fMRI, arterial spin-labelling and image analysis, and finally a chapter on the future of quantification. The physical principles behind each quantity are stated, followed by its biological significance. Practical techniques for measurement are given, along with pitfalls and examples of clinical applications. This second edition of this indispensable 'how to' manual of quantitative MR shows the MRI physicist and research clinician how to implement these techniques on an MRI scanner to understand more about the biological processes in the patient and physiological changes in healthy controls. Although focussed on the brain, most techniques are applicable to characterising tissue in the whole body. This book is essential reading for anyone who wants to use the gamut of modern quantitative MRI methods to measure the effects of disease, its progression, and its response to treatment. Features: The first edition was awarded the book prize for Radiology by the British Medical Association in 2004 Written by an authority in the field: Professor Tofts has an international reputation for quantification in MRI Gives specific ‘how to’ information for implementation of MRI measurement sequence techniques

Download or read book Targeted Muscle Reinnervation written by Todd A. Kuiken and published by Taylor & Francis. This book was released on 2013-07-23 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: Implement TMR with Your Patients and Improve Their Quality of LifeDeveloped by Dr. Todd A. Kuiken and Dr. Gregory A. Dumanian, targeted muscle reinnervation (TMR) is a new approach to accessing motor control signals from peripheral nerves after amputation and providing sensory feedback to prosthesis users. This practical approach has many advantage

Download or read book Radiosensitizers and Radiochemotherapy in the Treatment of Cancer written by Shirley Lehnert and published by CRC Press. This book was released on 2014-12-08 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiosensitizers and Radiochemotherapy in the Treatment of Cancer catalogs and describes the mechanism of action for entities characterized as radiosensitizers. Developments in the biological and physical sciences have introduced new radiosensitizers and defined novel targets for radiosensitization. As a result, a book about radiosensitization must now address a huge range of topics, covering everything from molecular oxygen and high Z elements to monoclonal antibodies and complex phytochemicals. At the molecular level, the understanding of the molecular consequences of DNA damage and the DNA damage response have informed the development of targeted radiosensitizers and shed light on the mode of action of radiochemotherapy protocols of known clinical efficacy. In this book the mechanisms of action at the molecular and cellular level are described for documented radiosensitizers including, where applicable, a brief history of their clinical use and most recent clinical results. In addition, the clinical context is addressed including the importance of factors such as dose and dose rate, normal tissue toxicity, and drug delivery. Intuitively organized by topic and application, the book includes extensive illustrations, end-of-chapter summaries, and a wealth of references.

Download or read book Medical Equipment Management written by Keith Willson and published by CRC Press. This book was released on 2013-12-07 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Know What to Expect When Managing Medical Equipment and Healthcare Technology in Your Organization As medical technology in clinical care becomes more complex, clinical professionals and support staff must know how to keep patients safe and equipment working in the clinical environment. Accessible to all healthcare professionals and managers, Medical Equipment Management presents an integrated approach to managing medical equipment in healthcare organizations. The book explains the underlying principles and requirements and raises awareness of what needs to be done and what questions to ask. It also provides practical advice and refers readers to appropriate legislation and guidelines. Starting from the medical equipment lifecycle, the book takes a risk-based approach to improving the way in which medical devices are acquired and managed in a clinical context. Drawing on their extensive managerial and teaching experiences, the authors explain how organizational structures and policies are set up, how funding is allocated, how people and equipment are supported, and what to do when things go wrong.

Download or read book Diagnostic Endoscopy written by Haishan Zeng and published by Taylor & Francis. This book was released on 2013-12-09 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combining a professional development course on diagnostic endoscopy from SPIE (the international society advancing light-based research) and the authors’ graduate course on biomedical optics, this work is written for researchers in medical optics and biomedical engineering as well as graduate medical optics students. It uses extensive examples/case studies to familiarize readers with the basics of endoscopic optics, the pros and cons of white light endoscopy and fluorescence endoscopy for diagnostic applications, and various microscopic endoscopy imaging modalities. It covers basic optics, details of design and biomedical uses, as well as microscopic endoscopy, and endoscopic spectroscopy.