Multivalency

Download or read book Multivalency written by Jurriaan Huskens and published by John Wiley & Sons. This book was released on 2018-02-05 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Connects fundamental knowledge of multivalent interactions with current practice and state-of-the-art applications Multivalency is a widespread phenomenon, with applications spanning supramolecular chemistry, materials chemistry, pharmaceutical chemistry and biochemistry. This advanced textbook provides students and junior scientists with an excellent introduction to the fundamentals of multivalent interactions, whilst expanding the knowledge of experienced researchers in the field. Multivalency: Concepts, Research & Applications is divided into three parts. Part one provides background knowledge on various aspects of multivalency and cooperativity and presents practical methods for their study. Fundamental aspects such as thermodynamics, kinetics and the principle of effective molarity are described, and characterisation methods, experimental methodologies and data treatment methods are also discussed. Parts two and three provide an overview of current systems in which multivalency plays an important role in chemistry and biology, with a focus on the design rules, underlying chemistry and the fundamental principles of multivalency. The systems covered range from chemical/materials-based ones such as dendrimers and sensors, to biological systems including cell recognition and protein binding. Examples and case studies from biochemistry/bioorganic chemistry as well as synthetic systems feature throughout the book. Introduces students and young scientists to the field of multivalent interactions and assists experienced researchers utilising the methodologies in their work Features examples and case studies from biochemistry/bioorganic chemistry, as well as synthetic systems throughout the book Edited by leading experts in the field with contributions from established scientists Multivalency: Concepts, Research & Applications is recommended for graduate students and junior scientists in supramolecular chemistry and related fields, looking for an introduction to multivalent interactions. It is also highly useful to experienced academics and scientists in industry working on research relating to multivalent and cooperative systems in supramolecular chemistry, organic chemistry, pharmaceutical chemistry, chemical biology, biochemistry, materials science and nanotechnology.

Download or read book Glycoscience written by Bertram O. Fraser-Reid and published by Springer Science & Business Media. This book was released on 2008-04-14 with total page 2847 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a reflection of the quantum leap that has been made in the study of glycostructures, the first edition of this book has been completely revised and updated. The editors give up-to-date information on glycostructures, their chemistry and chemical biology in the form of a completely comprehensive survey. Glycostructures play highly diverse and crucial roles in a myriad of organisms and important systems in biology, physiology, medicine, bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and the chemistry behind them. While many facts remain undiscovered, this MRW has been contributed to by a large number of the world’s leading researchers in the field.

Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Download or read book Applications of Multi-Criteria Decision-Making Theories in Healthcare and Biomedical Engineering written by Ilker Ozsahin and published by Academic Press. This book was released on 2021-03-25 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of Multi-Criteria Decision-Making Theories in Healthcare and Biomedical Engineering contains several practical applications on how decision-making theory could be used in solving problems relating to the selection of best alternatives. The book focuses on assisting decision-makers (government, organizations, companies, general public, etc.) in making the best and most appropriate decision when confronted with multiple alternatives. The purpose of the analytical MCDM techniques is to support decision makers under uncertainty and conflicting criteria while making logical decisions. The knowledge of the alternatives of the real-life problems, properties of their parameters, and the priority given to the parameters have a great effect on consequences in decision-making. In this book, the application of MCDM has been provided for the real-life problems in health and biomedical engineering issues. - Provides a comprehensive analysis and application multi-criteria decision-making methods - Presents detail information about MCDM and their usage - Covers state-of-the-art MCDM methods and offers applications of MCDM for health and biomedical engineering purposes

Download or read book Exemplary Ethics in Ancient Rome written by Rebecca Langlands and published by Cambridge University Press. This book was released on 2018-09-13 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The well-known mythographer Marina Warner has described the process of reading fairy tales and folktales as 'tasting the dragon's blood' - a magical and transformative process by which one's ears are opened to the voices of the past and of other worlds. Roman exempla, which constitute a national story-telling tradition, are very different in many ways from the dream-like fantasies of fairy-tales and other narrative folk traditions that have been the subject of Warner's studies. In (supposedly) true stories from history, battle-hardened warriors, noble maidens and honourable sons of the soil face impossible dangers, take terrible decisions and sacrifice their lives, their limbs and even their own children for the sake of justice, discipline and the Roman community. Yet for the ancient Romans too, hearing the blood-soaked stories of their ancestral heroes was an intimate and potent experience, and this 'taste of the hero's blood' had an intoxicating effect similar to the blood of Warner's dragon: evoking other worlds, shaping understanding of their own world"--

Download or read book Senses of the Empire written by Eleanor Betts and published by Taylor & Francis. This book was released on 2017-02-24 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Roman empire afforded a kaleidoscope of sensations. Through a series of multisensory case studies centred on people, places, buildings and artefacts, and on specific aspects of human behaviour, this volume develops ground-breaking methods and approaches for sensory studies in Roman archaeology and ancient history. Authors explore questions such as: what it felt like, and symbolised, to be showered with saffron at the amphitheatre; why the shape of a dancer’s body made him immediately recognisable as a social outcast; how the dramatic gestures, loud noises and unforgettable smells of a funeral would have different meanings for members of the family and for bystanders; and why feeling the weight of a signet ring on his finger contributed to a man’s sense of identity. A multisensory approach is taken throughout, with each chapter exploring at least two of the senses of sight, hearing, smell, taste and touch. The contributors’ individual approaches vary, reflecting the possibilities and the wide application of sensory studies to the ancient world. Underlying all chapters is a conviction that taking a multisensory approach enriches our understanding of the Roman empire, but also an awareness of the methodological problems encountered when reconstructing past experiences.

Download or read book Fragment-based Approaches in Drug Discovery written by Wolfgang Jahnke and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first systematic summary of the impact of fragment-based approaches on the drug development process provides essential information that was previously unavailable. Adopting a practice-oriented approach, this represents a book by professionals for professionals, tailor-made for drug developers in the pharma and biotech sector who need to keep up-to-date on the latest technologies and strategies in pharmaceutical ligand design. The book is clearly divided into three sections on ligand design, spectroscopic techniques, and screening and drug discovery, backed by numerous case studies.