Fast Facts Immuno Oncology

Download or read book Fast Facts: Immuno-Oncology written by Stephen Clarke and published by Karger Medical and Scientific Publishers. This book was released on 2021-07-07 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: The treatment of cancer has been revolutionized by therapies that modulate the immune system, with benefits for quality of life and survival. Standards of care have changed to reflect developments, but the area is moving fast. Keeping abreast of new therapies and trial data can be challenging. This second edition of 'Fast Facts: Immuno-Oncology' takes you from the fundamentals of immunology through to the new concepts of immunoediting and immunotherapy and likely future directions. Whether you have worked in oncology for decades and need a refresher or you are just starting out and need a crash course, this book provides all you need to know about immuno-oncology, concisely summarized. Table of Contents: • Components of the immune system • How cancers evade the immune system • How cancer immunotherapy works • Clinical use of immune checkpoint inhibitors • The future of immuno-oncology

Download or read book Fast Facts: Hypertension written by Graham A. MacGregor and published by Karger Medical and Scientific Publishers. This book was released on 2016-02-15 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypertension is the biggest cause of death and disability in the world, yet it remains underdiagnosed, undertreated and, in many cases, poorly controlled. As in the previous edition, 'Fast Facts: Hypertension' advises on: • accurate measurement of blood pressure and problems such as 'white-coat' hypertension • routine assessments for people with high blood pressure • other modifiable risk factors (smoking, high cholesterol levels etc.) • non-pharmacological measures (reducing salt, losing weight, increasing physical activity etc.) • rational and effective use of all drug treatments • identification of people with secondary hypertension • treatment of children, pregnant women, the elderly and patients with diabetes. Updates in this new edition include: • distinguishing between patients with primary (low renin) and secondary aldosteronism • greater use of home BP measurement in clinical decision-making • the latest thinking on BP treatment thresholds • new guidance on fourth-line therapy for resistant hypertension Sometimes dubbed 'the silent killer', hypertension rarely produces symptoms until it manifests as a heart attack or stroke, so early identification of the condition and appropriate management are vital. This practical readable refresher for every-day use supports better investigation and treatment of high blood pressure by primary care providers and better self-management by patients. Contents: • The dangers of raised blood pressure • Causes • Investigation • When to treat • How to treat • Special patient groups • Uncontrolled hypertension • Useful resources

Download or read book Fast Facts: Non-Small-Cell Lung Cancer written by Mary O'Brien and published by Karger Medical and Scientific Publishers. This book was released on 2016-08-22 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid developments in the classification, screening and treatment of non-small-cell lung cancer (NSCLC) are improving outcomes for patients with the disease. This insightful guide is designed to bring you up to speed with recent advances, including: • the latest CT-based screening and interval growth imaging techniques • proposed changes to the TNM classification system • the increasing trend for minimally invasive and lung-sparing surgery • stereotactic radiation for early-stage tumors • new targeted therapies • breakthroughs in personalized medicine. Today's developments will change tomorrow's standards of care. 'Fast Facts: Non-Small-Cell Lung Cancer' is important reading for all health professionals and medical trainees working in this fast-moving area.

Download or read book Fast Facts: Prostate Cancer written by Roger S. Kirby and published by Karger Medical and Scientific Publishers. This book was released on 2017-03-08 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prostate cancer is unusual among solid tumors in that the majority of affected men die with, rather than of, the disease. This presents many challenges to healthcare professionals and patients in terms of deciding if, when and how to intervene in order to control tumor growth and spread, thereby extending survival but without compromising quality of life. This is the ninth edition of 'Fast Facts: Prostate Cancer' since 1996, testament to the rapid changes in the field and the steadily improving outlook for patients. This new edition provides many key updates: • the Gleason grade grouping, which has valuable prognostic value • nomograms to evaluate risk • our rapidly expanding understanding of the genetics and underlying pathogenesis of prostate cancer and the development of genomic tests to help identify those at greatest risk of developing clinically significant disease • the continuing debate about the role of PSA in the screening, detection and monitoring of prostate cancer • advances in imaging techniques, particularly multiparametric MRI, which is improving the accuracy of biopsy and reducing the numbers of negative biopsies • the roles of drugs, surgery and radiotherapy in the treatment of prostate cancer at different stages, and our ever-improving understanding of when and how best to intervene, aided by improving understanding of the risk factors for disease progression. Primarily intended for primary care providers, specialist nurses, junior doctors and allied healthcare professionals, this highly readable resource provides a comprehensive overview of prostate cancer, enabling fully informed discussions with patients about this complex disease. Contents: • Epidemiology and pathophysiology • Diet, lifestyle and chemoprevention • Screening and early detection • Diagnosis, staging and prognostic indicators • Management of clinically localized disease • Managing recurrence after initial therapy • Management of metastatic prostate cancer • Management of castrate-resistant prostate cancer • Survivorship and treatment complications

Download or read book Fast Facts: Peripheral T-cell Lymphoma written by F. Foss and published by Karger Medical and Scientific Publishers. This book was released on 2019-06-20 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt: The peripheral T-cell lymphomas (PTCLs) are a heterogenous group of rare entities. Whilst cytogenetic and molecular identifiers are being identified, accurate diagnosis remains challenging, requiring careful, expert integration of the clinical and pathological findings. The treatment of PTCL is also challenging. Protocols for the different subtypes are only just beginning to emerge, hindered by the complexities of conducting trials in such uncommon and varied conditions. While first-line treatment with conventional chemotherapy is seldom curative, patients who achieve remission may be eligible for stem cell transplantation, offering the possibility of long-term disease control if not cure. Targeted biologics are also being developed as unique cytotoxic markers are identified. 'Fast Facts: Peripheral T-Cell Lymphomas' is a new title in the Fast Facts extensive hemato-oncology library, written by experts in this emerging field. This handbook will be useful to anyone involved in the care of patients with PTCL, including haematologists, oncologists, specialist nurses and primary care providers, raising awareness of these rare lymphomas and the current – and emerging – approaches to diagnosis and treatment.

Download or read book Fast Facts: Glioblastoma written by Mairéad McNamara and published by Karger Medical and Scientific Publishers. This book was released on 2020-02-26 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glioblastoma (also known as glioblastoma multiforme) is a malignant intrinsic tumor thought to arise from populations of stem/progenitor cells in the brain. It is the most common aggressive intrinsic brain tumor in adults, with the potential to spread rapidly within the brain. Patients with glioblastoma face a poor prognosis, with median overall survival of approximately 15 months. However, our growing understanding of the molecular biology of gliomas means that this outlook may be improving. The identification of clinically relevant subgroups defined by specific genetic mutations is challenging the traditional delineation between low- and high-grade gliomas that has been based on histological appearance and imaging. Indeed, it is becoming clear that, as a molecular entity, a glioblastoma, which by traditional classification is a grade IV glioma, may present with a lower grade initially and then become more aggressive – an important addition to the established concept. The care of a patient with a glioblastoma requires a coordinated approach delivered by a multidisciplinary team, with the aim of maintaining quality of life for as long as possible. Here, we provide a concise overview of the diagnosis and management of glioblastoma, as well as discussion of our emerging understanding of the molecular drivers that are helping us to delineate different patient subgroups. These subgroups will, hopefully, allow more targeted treatments in the future. This resource will be of interest to all those involved in caring for patients with this aggressive brain tumor, including neurologists, neurosurgeons, neuro-oncologists, radiation oncologists, palliative care specialists, specialist nurses and medical students. Contents: • Epidemiology, pathophysiology and classification • Clinical presentation • Diagnosis • Management • Treatment of associated conditions • Emerging research and treatment

Download or read book Fast Facts: Cholangiocarcinoma written by R.T. Shroff and published by Karger Medical and Scientific Publishers. This book was released on 2021-04-08 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cholangiocarcinomas (CCAs) are a group of heterogeneous tumors that have traditionally had poor prognosis. Despite being rare, the global incidence of CCA has increased dramatically over the last few decades. However, alongside this, there have been advancements in our understanding, diagnosis and treatment, improving the overall survival and quality of life of patients with advanced disease. This compact yet comprehensive review of CCA serves as a guide for physicians, oncologists, allied health professionals, scientists, patients and caregivers to update their knowledge of the most recent clinical developments and most promising areas of research. Table of Contents: • Pathophysiology, etiology and epidemiology • Diagnosis • Biliary drainage and supportive care • Surgical resection and transplantation • Translational research • Systemic therapy • Immunotherapy • Radiotherapy and photodynamic therapy