Barriers To Bioweapons

Download or read book Barriers to Bioweapons written by Sonia Ben Ouagrham-Gormley and published by Cornell University Press. This book was released on 2014-12-15 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: In both the popular imagination and among lawmakers and national security experts, there exists the belief that with sufficient motivation and material resources, states or terrorist groups can produce bioweapons easily, cheaply, and successfully. In Barriers to Bioweapons, Sonia Ben Ouagrham-Gormley challenges this perception by showing that bioweapons development is a difficult, protracted, and expensive endeavor, rarely achieving the expected results whatever the magnitude of investment. Her findings are based on extensive interviews she conducted with former U.S. and Soviet-era bioweapons scientists and on careful analysis of archival data and other historical documents related to various state and terrorist bioweapons programs.Bioweapons development relies on living organisms that are sensitive to their environment and handling conditions, and therefore behave unpredictably. These features place a greater premium on specialized knowledge. Ben Ouagrham-Gormley posits that lack of access to such intellectual capital constitutes the greatest barrier to the making of bioweapons. She integrates theories drawn from economics, the sociology of science, organization, and management with her empirical research. The resulting theoretical framework rests on the idea that the pace and success of a bioweapons development program can be measured by its ability to ensure the creation and transfer of scientific and technical knowledge. The specific organizational, managerial, social, political, and economic conditions necessary for success are difficult to achieve, particularly in covert programs where the need to prevent detection imposes managerial and organizational conditions that conflict with knowledge production.

Download or read book Biodefense in the Age of Synthetic Biology written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-01-05 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.

Download or read book A Short History of Biological Warfare written by W. Seth Carus and published by Government Printing Office. This book was released on 2017-08-03 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication gives a history of biological warfare (BW) from the prehistoric period through the present, with a section on the future of BW. The publication relies on works by historians who used primary sources dealing with BW. In-depth definitions of biological agents, biological weapons, and biological warfare (BW) are included, as well as an appendix of further reading on the subject. Related items: Arms & Weapons publications can be found here: https://bookstore.gpo.gov/catalog/arms-weapons Hazardous Materials (HAZMAT & CBRNE) publications can be found here: https://bookstore.gpo.gov/catalog/hazardous-materials-hazmat-cbrne

Download or read book Preventing a Biological Arms Race written by Susan Wright and published by MIT Press (MA). This book was released on 1990 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely sourcebook presents the essential technical, political, legal, and historical background needed for informed judgments about the recent expansion of military interest in the life sciences particularly in the weapons potential of the new biotechnology. Beyond providing a history and analysis of trends in these areas, "Preventing a Biological Arms Race also develops the case for strengthening national and international commitments to biological disarmament and proposes courses of action to achieve this goal. "In theory, " Susan Wright observes, "the menace of biological warfare should no longer be with us." Developing, producing, and stockpiling biological weapons are unconditionally banned by international treaty. EastWest military rivalry and confrontations in the Middle East have eroded confidence in the treaty regime, however. The advent of genetic engineering and other new biotechnologies has revived military interest in biological weaponry, generating concern about the potential weapons applications of biological research. The 15 contributions by experts from a wide range of disciplines include a history of U.S. biological warfare policy, analysis of the ethical issues posed by defensive biological warfare research, case studies of alleged violations of the international legal regime prohibiting biological weapons, reviews of that regime, and proposals for strengthening the barriers to biological warfare. A series of 14 appendices collect important data and documents related to biological weapons. Susan Wright is a historian of science at the Residential College of the University of Michigan where she directs the Science and Society Program. This book was prepared underthe sponsorship of the Council for Responsible Genetics.

Download or read book Innovation, Dual Use, and Security written by Jonathan B. Tucker and published by MIT Press. This book was released on 2012 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in disciplines such as biotechnology, nanotechnology, and neuropharmacology entail a "dual-use dilemma" because they promise benefits for human health and welfare yet pose the risk of misuse for hostile purposes. The emerging field of synthetic genomics, for example, can produce custom DNA molecules for life-saving drugs but also makes possible the creation of deadly viral agents for biological warfare or terrorism. The challenge for policymakers is to prevent the misuse of these new technologies without forgoing their benefits . Innovation, Dual Use, and Security offers a systematic approach for managing the dual-use dilemma. The book presents a "decision framework" for assessing the security risks of emerging technologies and fashioning governance strategies to manage those risks. This framework is applied to fourteen contemporary case studies, including synthetic genomics, DNA shuffling and directed evolution, combinatorial chemistry, protein engineering, immunological modulation, and aerosol vaccines. The book also draws useful lessons from two historical cases: the development of the V-series nerve agents in Britain and the use and misuse of LSD by the U.S. Army and the CIA. Innovation, Dual Use, and Security offers a comprehensive, multifaceted introduction to the challenges of governing dual-use technologies in an era of rapid innovation. The book will be of interest to government officials and other practitioners as well as to students and scholars in security studies, science and technology studies, biology, and chemistry.

Download or read book The Soviet Biological Weapons Program written by Milton Leitenberg and published by Harvard University Press. This book was released on 2012-06-29 with total page 956 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first attempt to understand the full scope of the USSR’s offensive biological weapons research, from inception in the 1920s. Gorbachev tried to end the program, but the U.S. and U.K. never obtained clear evidence that he succeeded, raising the question whether the means for waging biological warfare could be present in Russia today.

Download or read book Long Shot written by Kendall Hoyt and published by Harvard University Press. This book was released on 2012-02-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: At the turn of the twenty-first century, the United States contended with a state-run biological warfare program, bioterrorism, and a pandemic. Together, these threats spurred large-scale government demand for new vaccines, but few have materialized. A new anthrax vaccine has been a priority since the first Gulf War, but twenty years and a billion dollars later, the United States still does not have one. This failure is startling. Historically, the United States has excelled at responding to national health emergencies. World War II era programs developed ten new or improved vaccines, often in time to meet the objectives of particular military missions. Probing the history of vaccine development for factors that foster timely innovation, Kendall Hoyt discovered that vaccine innovation has been falling, not rising, since World War II. This finding is at odds with prevailing theories of market-based innovation and suggests that a collection of nonmarket factors drove mid-century innovation. Ironically, many late-twentieth-century developments that have been celebrated as a boon for innovation—the birth of a biotechnology industry and the rise of specialization and outsourcing—undercut the collaborative networks and research practices that drove successful vaccine projects in the past. Hoyt’s timely investigation teaches important lessons for our efforts to rebuild twenty-first-century biodefense capabilities, especially when the financial payback for a particular vaccine is low, but the social returns are high.