Antibiotic Pharmacodynamics

Download or read book Antibiotic Pharmacodynamics written by John C. Rotschafer and published by Humana. This book was released on 2016-03-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text offers state of the art contributions written by world renown experts which provide an extensive background on specific classes of antibiotics and summarize our understanding as to how these antibiotics might be optimally used in a clinical situation. The book explores pharmacodynamics methods for anti-infective agents, pharmacodynamics of antibacterial agents and non-antibacterial agents, as well as pharmacodynamic considerations and special populations. As part of the Methods in Pharmacology and Toxicology series, chapters include detailed insight and practical information for the lab. Comprehensive and cutting-edge, Antibiotic Pharmacodynamics serves as an ideal reference for scientists investigating advances in antibiotic pharmacodynamics now finding their way into the antibiotic development process used for licensing new antibiotics.

Download or read book Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics written by Alexander A. Vinks and published by Springer Science & Business Media. This book was released on 2013-11-23 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be of considerable value in understanding drug action, defining optimal dosing regimens, and in making predictions under new or changing pre-clinical and clinical circumstances. Not surprisingly, pharmacokinetic-pharmacodynamic modeling concepts are increasingly applied in both basic and clinical research as well as in drug development. The book will be designed as a reference on the application of pharmacokinetic-pharmacodynamic principles for the optimization of antimicrobial therapy, namely pharmacotherapy, and infectious diseases. The reader will be introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, and the translation of in vitro and animal model data to basic research and clinical situations in humans.

Download or read book Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill written by Andrew A. Udy and published by Springer. This book was released on 2017-09-18 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides unique insights into the issues that drive modified dosing regimens for antibiotics in the critically ill. Leading international authors provide their commentary alongside a summary of existing evidence on how to effectively dose antibiotics. Severe infection frequently necessitates admission to the intensive care unit (ICU). Equally, nosocomial sepsis often complicates the clinical course in ICU. Early, appropriate application of antibiotic therapy remains a cornerstone of effective management. However, this is challenging in the critical care environment, given the significant changes in patient physiology and organ function frequently encountered. Being cognisant of these factors, prescribers need to consider modified dosing regimens, not only to ensure adequate drug exposure, and therefore the greatest chance of clinical cure, but also to avoid encouraging drug resistance.

Download or read book Practical Implementation of an Antibiotic Stewardship Program written by Tamar F. Barlam and published by Cambridge University Press. This book was released on 2018-04-26 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical reference guide from experts in the field details why and how to establish successful antibiotic stewardship programs.

Download or read book Antibacterial Therapy: Achievements, Problems and Future Perspectives written by W.-D. Busse and published by Springer. This book was released on 1997-10 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume reviews important contributions in the area of antibacterial research with regard to current status and future therapy problems, especially in the field of beta-lactams, antibiotics, quinolones and other classes of antimicrobials. Possible future tragets and new strategies are discussed from a scientific as well as pharmacoeconomic point of view to meet the needs of the future.

Download or read book Antimicrobial Therapy I written by and published by . This book was released on 1995 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Pharmacist's Guide to Antimicrobial Therapy and Stewardship written by Sarah M. Wieczorkiewicz and published by ASHP. This book was released on 2015-12-15 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: When a patient comes in with a suspected infectious disease, knowledge is power. Now this knowledge is simplified, comprehensive and easy to find. The Pharmacist's Guide to Antimicrobial Therapy and Stewardship puts all the necessary information in one place, including: Evaluating potentially infected patients Identifying the infection's suspected source and related organisms Comparing the range of anti-infectives Knowing the factors that impact treatment Developing an antimicrobial stewardship program A step-wise approach walks logically from overall key concepts to disease- and drug-specific information. Disease states are summarized for easy reference. Tables make it easy to evaluate recommended treatment options. In infectious disease management, when answers are seldom black and white, this guide helps pharmacists make confident decisions.