Transcription And Translation In Health And Disease

Download or read book Transcription and Translation in Health and Disease written by Manoj Garg and published by Elsevier. This book was released on 2023-01-30 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transcription and Translation in Health and Disease provides a detailed overview of the regulators underlying transcription and translation in relation to a variety of human diseases and disorders. Beginning with an introduction into the current perspectives relating to these processes in human disease, the book expands to focus on specific mechanisms underlying conditions such as arthritis, cancer, neurological disorders, diabetes and cardiovascular disease. This book considers RNA processing and related mechanisms in eukaryotes including RNA splicing, RNA binding proteins, RNA interference, microRNAs, RNA editing, transcription factors, RNAi screening, CRISPR activation, CRISPR-Cas9 interference, and post-translational modifications. It provides a structured and detailed overview of the various regulators underlying molecular processes and their impact on health and disease, equipping readers with the necessary knowledge for further investigation in the areas of treatment and therapeutic intervention. - Discusses the role played by transcription and translational regulation in various diseases, including cancer, diabetes, cardiovascular disease and neurological disease - Considers a range of post-transcriptional regulators, including RNA-binding proteins, non-coding RNAs, epigenetic modifiers, alternative splicing and telomerase-binding proteins - Covers the topic from fundamental knowledge to the latest developments in clinical application - Includes a section dedicated to therapeutic applications

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book RNA-Based Regulation in Human Health and Disease written by and published by Academic Press. This book was released on 2020-08-19 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA beyond humans, tools and technologies for RNA research (wet lab and computational) and future prospects for RNA-based diagnostics and therapeutics. One of the core strengths of the book includes spectrum of disease-specific chapters from experts in the field highlighting RNA-based regulation in metabolic & neurodegenerative disorders, cancer, inflammatory disease, viral and bacterial infections. We hope the book helps researchers, students and clinicians appreciate the role of RNA-based regulation in genome regulation, aiding the development of useful biomarkers for prognosis, diagnosis, and novel RNA-based therapeutics. - Comprehensive information of non-canonical RNA-based genome regulation modulating human health and disease - Defines RNA classes with special emphasis on unexplored world of noncoding RNA at different hierarchies - Disease specific role of RNA - causal, prognostic, diagnostic and therapeutic - Features contributions from leading experts in the field

Download or read book Fundamentals of Biochemistry Medical Course and Step 1 Review written by David DiTullio and published by McGraw Hill Professional. This book was released on 2018-11-02 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The biochemistry/USMLE® review you’ve been waiting for . . . clear, concise, high yield, and clinically relevant INCLUDES AN ONLINE VIDEO LECTURE FOR EVERY CHAPTER! The goal of Fundamentals of Biochemistry: Medical Course & Step 1 Review is to make biochemistry an approachable, clinically relevant subject for your first years of medical school, and, most importantly, when you prepare to take the USMLE® Step 1 examination. The authors believe that when biochemistry is put in a clinical context, learning and understanding it becomes much less complicated, as all the pieces of the “puzzle” fall into place. A SELF-CONTAINED, HIGH-YIELD GUIDE UNLIKE ANY OTHER You will find Fundamentals of Biochemistry: Medical Course & Step 1 Review to be a self-contained guide to high-yield biochemistry, with a strong focus on the topics you are most likely to see on the USMLE® Step 1 exam. You can select any chapter and find a self-contained summary of the relevant topic. The authors begin with the basics of the cell and DNA, and protein synthesis, then cover the central aspects of metabolism, and finish with nutrition and genetics. EASY-TO-ABSORB CHAPTERS ENHANCED BY COMPANION ONLINE VIDEOS The information is delivered in a simple outline format that pinpoints the high-yield information you need to know. Each chapter is also presented as a lecture, in video format, so you can review the topic in real time and add additional notes as you learn each topic or review them later.

Download or read book The Human Body in Health & Disease - Softcover6 written by Kevin T. Patton and published by Elsevier Health Sciences. This book was released on 2013-01-01 with total page 825 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rev. ed. of: The human body in health & disease / Gary A. Thibodeau, Kevin T. Patton. 5th ed. c2010.

Download or read book Translational Systems Medicine and Oral Disease written by Stephen T. Sonis and published by Academic Press. This book was released on 2019-09-14 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Systems Medicine and Oral Disease bridges the gap between discovery science and clinical oral medicine, providing opportunities for both the scientific and clinical communities to understand how to apply recent findings in cell biology, genomic profiling, and systems medicine to favorably impact the diagnosis, treatment and management of oral diseases. Fully illustrated chapters from leading international contributors explore clinical applications of genomics, proteomics, metabolomics, microbiomics and epigenetics, as well as analytic methods and functional omics in oral medicine. Disease specific chapters detail systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease, and autoimmune disease, among others. In addition, the book emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology and primary care. - Presents the work of leading international researchers and clinicians who speak on the clinical applications of genomics, proteomics, metabolomics, microbiomics, and epigenetics, as well as analytic methods and functional omics in oral medicine - Provides full-color, richly illustrated chapters that examine systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease and autoimmune diseases - Includes clinical case studies that illustrate examples of oral disease diagnostics and management, highlighting points of key importance for the reader - Emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers, and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology, and primary care

Download or read book The Human Body in Health & Disease - E-Book written by Kevin T. Patton and published by Elsevier Health Sciences. This book was released on 2023-01-03 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, The Human Body in Health & Disease, 8th Edition makes it easier to understand how the body works, both in typical conditions and when things change. Its easy-to-read writing style, more than 500 full-color illustrations, and unique Clear View of the Human Body transparencies keep you focused on the principles of anatomy, physiology, and pathology. Key features are Connect It! with bonus online content, concept maps with flow charts to simplify complex topics, and chapter objectives and active learning sections. From noted educator Kevin Patton, this book presents A&P in a way that lets you know and understand what is important. - More than 500 full-color photographs and drawings illustrate the most current scientific knowledge and bring difficult concepts to life. The beautifully rendered illustrations are unified by a consistent color key and represent a diversity of human identity. - A conversational writing style is paired with "chunked" content, making it easy to read and comprehend. - UNIQUE! Creative page design uses color backgrounds to organize information in a more inviting, accessible, and motivating way to enhance learning. - UNIQUE! The full-color, semi-transparent Clear View of the Human Body permits the on-demand virtual dissection of typical male and female human bodies along several body planes. This 22-page insert contains a series of transparencies that allows you to peel back the layers of the body anterior-to-posterior and posterior-to-anterior. - Language of Science/Language of Medicine word lists at the beginning of chapters present key terms, pronunciations, and word-part translations to help you become familiar with new and complex terminology. - Animation Direct feature throughout the text guides you to state-of-the-art animations on the companion Evolve website to provide dynamic visual explanations of key concepts. - Active Concept Maps offer animated, narrated walk-throughs of concept maps to clarify the text narrative and provide you with clear examples of how to build your own concept maps.