Lead Compounds From Medicinal Plants For The Treatment Of Neurodegenerative Diseases

Download or read book Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases written by Christophe Wiart and published by Academic Press. This book was released on 2013-12-16 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases is the second volume in the series, Pharmaceutical Leads from Medicinal Plants. This book includes key pharmacological and chemical evidence to support the selection of promising pre-clinical candidates for the treatment of neurodegenerative diseases. This important addition to the natural product and drug discovery literature contains the history, synonyms, medicinal uses, phytopharmacology, pre-clinical potential, and rationale for each plant selected. By providing critical evaluation of pharmacological data, mechanisms of action, and structural requirements for the development of future neuroprotective agents, this comprehensive reference is a beneficial resource for industry and academic scientists whose research focuses on neurodegenerative drug discovery and development. - Incorporates compelling biological activity data and preclinical structure-activity relationships to help you choose promising lead molecules for further research - Includes primary source references to the most recent natural product discoveries in the field of neuroprotection in order to promote new drug discovery in this area - Contains detailed discussions of important neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease - Each plant section includes a critical evaluation of pharmacological, chemical, and toxicological evidence to support the use of the compound in drug discovery research in neurodegeneration

Download or read book Phytochemicals as Lead Compounds for New Drug Discovery written by Chukwuebuka Egbuna and published by Elsevier. This book was released on 2019-09-07 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytochemicals as Lead Compounds for New Drug Discovery presents complete coverage of the recent advances in the discovery of phytochemicals from medicinal plants as models to the development of new drugs and chemical entities. Functional bioactive compounds of plant origin have been an invaluable source for many human therapeutic drugs and have played a major role in the treatment of diseases around the world. These compounds possess enormous structural and chemical diversity and have led to many important discoveries. This book presents fundament concepts and factors affecting the choice for plant-based products, as well as recent advances in computer-aided drug discovery and FDA drug candidacy acceptance criteria. It also details the various bioactive lead compounds and molecular targets for a range of life-threatening diseases including cancer, diabetes, and neurodegenerative diseases. Written by a global team of experts, Phytochemicals as Lead Compounds for New Drug Discovery is an ideal resource for drug developers, phytochemists, plant biochemists, food and medicinal chemists, nutritionists and toxicologists, chemical ecologists, taxonomists, analytical chemists, and other researchers in those fields. It will also be very valuable to professors, students, and researchers in this domain. - Presents fundamental concepts and factors affecting choice for plant-based products - Details the FDA drug candidacy acceptance criteria, including bottlenecks and way forward - Highlights recent advances in computational-based drug discovery - Focuses on the discovery of new drugs and potential druggable targets for the treatment of chronic diseases of world importance

Download or read book The Benefits of Natural Products for Neurodegenerative Diseases written by M. Mohamed Essa and published by Springer. This book was released on 2016-09-20 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focuses on the effects of natural products and their active components on brain function and neurodegenerative disease prevention. Phytochemicals such as alkaloids, terpenes, flavanoids, isoflavones, saponins etc are known to possess protective activity against many neurological diseases. The molecular mechanisms behind the curative effects rely mainly on the action of phytonutrients on distinct signaling pathways associated with protein folding and neuro-inflammation. The diverse array of bioactive nutrients present in these natural products plays a pivotal role in prevention and cure of various neurodegenerative diseases, disorders, or insults, such as Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, traumatic brain injury, and other neuronal dysfunctions. However, the use of these antioxidants in the management of neurodegenerative conditions has so far been not well understood. This is a comprehensive collection addressing the effects on the brain of natural products and edible items such as reservatrol, curcumin, gingerol, fruits, vegetables, nuts, and marine products.

Download or read book Bioactive Compounds in Nutraceutical and Functional Food for Good Human Health written by Kavita Sharma and published by BoD – Books on Demand. This book was released on 2021-04-07 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioactive compounds are abundant in nature, particularly in plants, which have the capacity to synthesize phenolics, flavonoids, caffeine, carotenoids, and much more. Different bioactive compounds can change or alter the life process due to their different biological activities. This book examines bioactive compounds and their sources, structures, and potential uses in various industries, including pharmaceuticals, medicine, cosmetics, and food processing.

Download or read book Parkinson's Disease in the Older Patient written by Jeremy R. Playfer and published by Radcliffe Publishing. This book was released on 2008 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text represents a detailed guide to the holistic assessment and the management of older patients with Parkinson's disease, based on current concepts in the management of chronic diseases and the caring strategies required in the four stages.

Download or read book Liquorice written by Münir Öztürk and published by Springer. This book was released on 2018-03-19 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Licorice (Glycyrrhiza) is one of the most widely used in foods, herbal medicine and one of the extensively researched medicinal plants of the world. In traditional medicine licorice roots have been used against treating many ailments including lung diseases, arthritis, kidney diseases, eczema, heart diseases, gastric ulcer, low blood pressure, allergies, liver toxicity, and certain microbial infections. Licorice extract contains sugars, starch, bitters, resins, essential oils, tannins, inorganic salts and low levels of nitrogenous constituents such as proteins, individual amino acids, and nucleic acids. A large number of biologically active compounds have been isolated from Glycyrrhiza species, where triterpene, saponins and flavonoids are the main constitutes which show broad biological activities. The present book will discuss the botany, the commercial interests as well as the recent studies on the phytochemistry and pharmacology of licorice. It will also describe the side effects and toxicity of licorice and its bioactive components, an underrepresented subjects of importance. It will be the first book to present global perspectives of licorice in detail. It will serve as a carefully researched introduction for students, healthcare practitioners, botanists and plant biochemists; full of historical background and bridges the gap between botany, ecology, pharmacology, as well as treatment of diseases.

Download or read book Botanical Medicine for Women's Health E-Book written by Aviva Romm and published by Elsevier Health Sciences. This book was released on 2017-01-25 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: Use herbal medicines to treat women at any stage of life! Botanical Medicine for Women's Health, 2nd Edition provides an evidence-based, patient-centered approach to botanical interventions for many different medical conditions. More than 150 natural products are covered, showing their benefits in gynecologic health, fertility and childbearing, and menopausal health. This edition includes new full-color photos of herbal plants along with a discussion of the role of botanicals in healthy aging. Written by Aviva Romm, an experienced herbalist, midwife, and physician, this unique guide is an essential resource for everyday practice of herbal medicine. Winner of the 2010 American Botanical Council's James A. Duke Excellence in Botanical Literature Award! - Current, evidence-based information covers more than 150 botanicals for over 35 different conditions. - Case studies provide realistic scenarios and help you apply the content to the real world. - Treatment and formula boxes summarize the most important information. - Color illustrations and photographs of plants enable you to identify herbs visually as well as by substance make-up. - Logical chapter organization begins with the principles of herbal medicine and then covers women's health conditions organized chronologically by lifecycle, from teen and reproductive years to midlife and mature years. - Appendices include practical, at-a-glance information on common botanical names, chemical constituents of medicinal plants, and a summary table of herbs for women's health. - NEW! Updates reflect the latest research and the most current information. - NEW Full-color design and detailed, professional color photos of plants make this a unique, essential resource. - NEW! Coverage of the role of botanicals in healthy aging for women features phytoestrogens, Ayurvedic/Chinese herbs, and discussions of health promotion.